Acute Effects Of 24-h Sleep Deprivation On Salivary Cortisol And Testosterone Concentrations And Testosterone To Cortisol Ratio Following Supplementation With Caffeine Or Placebo

Caffeine has become a popular ergogenic aid amongst athletes and usage to improve athletic performance has been well documented. The effect of caffeine on anabolic and catabolic hormones in a sleep-deprived state has had little investigation to date. The purpose of the current study was to investigate the potential of caffeine to offset the effects, if any, of short-term sleep deprivation and exercise on an athlete’s testosterone and cortisol concentrations via salivary technique. Eleven competitive male athletes volunteered to be part of this prospective double-blinded study. Three test days were scheduled for each athlete; one non-sleep deprived, one sleep-deprived with caffeine supplementation (6 mg.kg-1) and one sleep-deprived with placebo ingestion. Sleep deprivation was defined as 24-h without sleep. Each test day was composed of 2 aerobic components: a modified Hoff test and a Yo-Yo test. Testosterone and cortisol concentrations were measured via salivary analysis at 4 different time-points; T1 to T4, representing baseline, and pre- and post-aerobic components, respectively. Overall no significant differences were detected comparing the different sleep states for testosterone or cortisol concentrations. A trend existed whereby the sleep-deprived with caffeine ingestion state mirrored the non-sleep deprived state for cortisol concentration. Therefore, caffeine supplementation may have potential benefits for athletes during short-term aerobic exercise when sleep-deprived. An increase in mean testosterone concentration post-aerobic exercise was only observed in the sleep-deprived with caffeine ingestion state.

Mc Donald, Ciaran K.; Moore, Joss; Mc Intyre, Alan; Carmody, Kevin; and Donne, Bernard (2017) “Acute Effects Of 24-h Sleep Deprivation On Salivary Cortisol And Testosterone Concentrations And Testosterone To Cortisol Ratio Following Supplementation With Caffeine Or Placebo,” International Journal of Exercise Science: Vol. 10 : Iss. 1, Pages 108 – 120.

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